Introduction To Bioinformatics
(Arthur M. Lesk)
On 26 June 2000, the completion of thedraft sequence of the Human Genome saw the sciences of biology andmedicine change forever. It promised new insights into our geneticmake-up, how our genes shape who we are, and how we function, and newpossibilities for an improved quality of life, exploiting new knowledgeto design novel, more effective drugs. At the heart of thisbreakthrough lies a scientific discipline which is now one of the mostimportant information gathering, data-mining, and knowledge-buildingtools in current research and healthcare development: bioinformatics.Written by a pioneer of the use of bioinformatics in research,Introduction to Bioinformatics 2/e introduces the student to the powerof bioinformatics as a set of scientific tools. The book explains howto access the data archives of genomes and proteins, and the kind ofquestions these data and tools can answer - how to make inferences fromthe data archives, to make connections among them, and to derive usefuland interesting predictions. Retaining and enhancing the rich pedagogyand lucid presentation of the first edition, the book is accompanied bya fully integrated Companion Web Site, encouraging students to explorethe computational tools of bioinformatics in a relevant and stimulatingway. Companion Web Site - Figures from the book available to download,to facilitate lecture slide preparation - Web link library of all URLscited in the book, and hyperlinks to a wide range of further readingarticles, to give students ready access to these resources - Links to PDB structures of all proteins cited in the book, to enable students toinvestigate the 3D structures of proteins in a visual, interactive way- Data from the book in computer-readable form, which is available forinstant use to facilitate hands-on learning by the student - Guidanceto help students answer problems from the text, to support andencourage self-learning
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